Isolation of soyasaponin I as an inhibitor for glycolate oxidase.

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Isolation of human renin inhibitor from soybean: soyasaponin I is the novel human renin inhibitor in soybean.

We found human renin inhibitory activity in soybean and isolated the active compound, soybean renin inhibitor (SRI). The physico-chemical data on the isolated SRI were identical with those of soyasaponin I. SRI showed significant inhibition against recombinant human renin, with an IC(50) value of 30 microg/ml. Kinetic studies with SRI indicated partial noncompetitive inhibition, with a K(i) val...

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ژورنال

عنوان ژورنال: Agricultural and Biological Chemistry

سال: 1981

ISSN: 0002-1369,1881-1280

DOI: 10.1271/bbb1961.45.2637